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9-OH Risperidone D4

Catalog no. AN-14176
Name 9-OH Risperidone D4
CAS No. 1020719-55-4
Synonyms 9-Hydroxyrisperidone D4; 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl-d4]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; Invega-d4; Paliperidone-d4; R 76477-d4; RO 76477-d4; Risperidone Imp. C (EP)-d4
Purity 98+%
Formula C23H23D4FN4O3
FW 430.52
Storage -20°C Freezer
Shipping Off-White to Pale Yellow Solid
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Description

A deuterated metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. An internal standard suitable for use in LC/MS or GC/MS applications including forensic analysis, clinical toxicology, urine drug testing, or isotope dilution methods. Also known as paliperidone, 9-Hydroxyrisperidone is sold under the brand name Invega, an atypical antipsychotic used for acute and maintenance treatment of schizophrenia.

References

Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005)