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Calcipotriol

Catalog No. V09119
Name Calcipotriol
Synonyms Calcipotriene;Dovonex; Sorilux; Calcitrene; MC-903; Daivonex; Psorcutan
CAS No. 112965-21-6
Purity 99+%
Formula
C27H40O3
Mol. Weight 412.60
Storage -20°C Freezer
Appearance White solid
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Additional information

Description

Calcipotriol, a vitamin D3 analog, acts not only to inhibit cell proliferation and enhance cell differentiation in the skin of patients with psoriasis, but also appears to have effects on immunologic markers that are thought to play a role in the etiology of the disease.

References

Binderup, L. and Bramm, E.: Biochem. Pharmacol., 37, 889 (1988), Valaja, T., et al.: Biochem. Pharmacol., 40, 1827 (1990), Ashcroft, D.M., et al.: Brit Med. J., 320, 963 (2000), Ghoreishi, M., et al.: J. Immunol., 182, 6071 (2009), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008).