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Retinoic Acid

Catalog No. V09134
Name Retinoic Acid
Synonyms Tretinoin; ATRA; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid; Vitamin A Acid; all-trans Retinoic Acid; NSC 122578; NSC 122758
CAS No. 302-79-4
Purity 99+%
Formula C20H28O2
Mol. Weight 300.4
Storage -20°C Freezer
Appearance Orange solid
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Description

Retinoic acid (RA) has been used for the differentiation of embryonic stem cells into motor neurons. It has been used for the differentiation of Xenopus ectoderm into pancreas. It has also been used to study epigenetic regulation by RARα (retinoic acid receptor α). It has been used to study RA signaling of prospermatogonia transition into spermatogonia.

References

1. Duong, V. and Rochette-Egly, C. The molecular physiology of nuclear retinoic acid receptors. From health to disease. Biochim Biophys. Acta. 1812(8), 1023-1031 (2011); 2. Rochette-Egly, C. and Germain, P. Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs). Nucl. Recept. Signal 7, 1-18 (2009); 3. Dollé, P. Developmental expression of retinoic acid receptors (RARs). Nucl. Recept. Signal 7, 1-13 (2009).