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Labelled Reference Standards, Stable Isotopes, Drug Substances, Drug Impurities, Metabolites, Bio chemicals and more..

Organic and Medicinal Chemistry Services

Custom Synthesis & More

Process Development

Scale-Up

GMP Manufacturing

Analytical Services

CRO Laboratories Inc. is a leading Contract Research Organization (CRO) headquartered in Dallas, Texas, providing end-to-end chemistry services to pharmaceutical, biotechnology, academic, and government organizations worldwide. Our core expertise includes synthetic chemistry, medicinal chemistry, custom synthesis, route scouting, process development, and process optimization, supporting drug discovery, preclinical development, scale-up, and commercialization programs.
CRO Laboratories Inc. is also a trusted global manufacturer and supplier of deuterium-labeled and ¹³C-labeled compounds, stable isotope-labeled drug substances, analytical reference standards, pharmaceutical standards, drug impurities, metabolites, active pharmaceutical ingredients (APIs), and specialty research chemicals. With over 4,000 in-stock catalog products and flexible production capabilities from milligram to kilogram scale, we deliver high-quality, reliable, fast-turnaround, and cost-effective solutions that accelerate research, regulatory filings, and commercial success.

Contract Services

Medicinal Chemistry

  • Design/synthesis of custom libraries
  • Lead generation and optimization
  • Synthesis of organic scaffolds
  • Synthesis of pro-drugs and new chemical entities

Process Development

  • Route design and optimization
  • Process optimization and scale up to kg to multi-kg scale
  • Large scale synthesis and purifications
  • Production of pharmaceutical raw materials

Analytical Services

  • Analytical and preparatory HPLC method development
  • GC and LC-MS analysis
  • Optical rotations and chiral separation
  • Purity determinations by HPLC

Custom Synthesis

  • Synthesis of intermediates
  • Synthetic route development
  • Metabolites synthesis/characterization
  • Impurities isolation, synthesis and characterization

Scale-Up

  • Scale-up from gm to kg non-GMP
  • Scale-up from gm to kg GMP
  • Synthesis of organic scaffolds
  • Synthesis of pro-drugs, new chemical entities and advanced intermediates for preclinical studies

GMP Manufacturing

  • Multi-kg services of pharmaceutical intermediates, active pharmaceutical ingredients (APIs), new chemical entities (NCEs) as well as cGMP manufacturing of drug substances

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