11-Cis-Acitretin

Catalog No.	V09146
Name	11-Cis-Acitretin
Synonyms	(2E,4Z,6E,8E)-9-(4-Methoxy-d3-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid
CAS No.	1067630-53-8
Purity	99+%
Formula	C₂₁H₂₆O₃
Mol. Weight	329.45
Storage	-20°C Freezer
Appearance	Yellow Solid
MSDS	Inquire

$150.00 – $950.00

Additional information

Description	Isomer of Acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.
References	1. Berbis Ph, et al.: Arch Dermatol Res (1988) 280:388-389. 2. Maier H, Honigsmann H: Concentration of etretinate in plasma and subcutaneous fat after long-term acitretin. Lancet 348:1107, 1996. 3. Geiger JM, Walker M: Is there a reproductive safety risk in male patients treated with acitretin (Neotigason/ Soriatane)? Dermatology 205:105-107, 2002.