Additional information
Description | 13-cis-Acitretin is cis isomer of acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis. |
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References | 1. Berbis Ph, et al.: Arch Dermatol Res (1988) 280:388-389. |