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25-Hydroxyvitamin D2-d6

Catalog No. V09112
Name 25-Hydroxyvitamin D2-d6
Synonyms Ercalcidiol-d6; 25-Hydroxyergocalciferol-d6; 25-Hydroxycalciferol-d6
CAS No. 21343-40-8 (Unlabeled)
Purity 99+%
Formula C28H38D6O2
Mol. Weight 418.68
Storage -20°C Freezer
Appearance White solid
MSDS Inquire

$650.00$4,500.00

Additional information

Description

Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity. Vitamin D2 is produced in fungi, including yeast, from ergosterol in response to ultraviolet radiation. 25-hydroxy Vitamin D2 is an intermediate produced from vitamin D2 by cytochrome P450 isoforms in vertebrates. It is subsequently metabolized to 1,25-dihydroxy vitamin D2, which is an agonist for the vitamin D receptor.

References

1. Jones et al (1976) An in vitro study of vitamin D2 hydroxylases in the chick. J.Biol.Chem. 251 24 PMID: 1081537.
2. Barnes, P., et al.: J. Clin. Invest., 83, 1527 (1989), Holick, M., et al.: J. Cell Biochem., 88(2), 296 (2003), Maunsell, Z., et al.: Clin. Chem., 51, 1683 (2005)