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Catalog No. V09148
Name 9-Cis-Acitretin
Synonyms (2E,4E,6Z,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid
CAS No. 419534-31-9
Purity 99+%
Formula C21H26O3
Mol. Weight 326.43
Storage -20°C Freezer
Appearance Yellow Solid
MSDS Inquire



Additional information


13-cis-Acitretin is cis isomer of acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.


1. Berbis Ph, et al.: Arch Dermatol Res (1988) 280:388-389.
2. Maier H, Honigsmann H: Concentration of etretinate in plasma and subcutaneous fat after long-term acitretin. Lancet 348:1107, 1996.
3. Geiger JM, Walker M: Is there a reproductive safety risk in male patients treated with acitretin (Neotigason/ Soriatane)? Dermatology 205:105-107, 2002.