Name: 9-Cis-Acitretin
Availability: InStock

9-Cis-Acitretin

Catalog No.

V09148

Name

9-Cis-Acitretin

Synonyms

(2E,4E,6Z,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid

CAS No.

419534-31-9

Purity

99+%

Formula

C₂₁H₂₆O₃

Mol. Weight

326.43

Storage

-20°C Freezer

Appearance

Yellow Solid

MSDS

Inquire

$50.00 – $325.00

Additional information

Description	13-cis-Acitretin is cis isomer of acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.
References	1. Berbis Ph, et al.: Arch Dermatol Res (1988) 280:388-389. 2. Maier H, Honigsmann H: Concentration of etretinate in plasma and subcutaneous fat after long-term acitretin. Lancet 348:1107, 1996. 3. Geiger JM, Walker M: Is there a reproductive safety risk in male patients treated with acitretin (Neotigason/ Soriatane)? Dermatology 205:105-107, 2002.

9-Cis-Acitretin