Additional information
Biological Activity | A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic. |
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References | De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987) |