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N-Boc-glycine methyl ester

Catalog No. H171364
Name N-Boc-glycine methyl ester
Synonyms boc-glycine methyl ester, boc-gly-ome, n-tert-butoxycarbonyl glycine methyl ester, n-boc-glycine methyl ester, boc-glycinemethylester, methyl 2-tert-butoxycarbonyl amino acetate, methyl n-tert-butoxycarbonyl glycinate, glycine, n-1,1-dimethylethoxy carbonyl-, methyl ester, methyl tert-butoxycarbonyl amino acetate
CAS No. 31954-27-5
Purity 98+%
Formula C8H15NO4
Mol. Weight 189.21
Storage Room temperature
Appearance Liquid
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Additional information

Description

N-Boc-glycine-methyl-ester is a chemical compound commonly used in peptide synthesis and organic chemistry. It is derived from glycine, the simplest amino acid, and features a tert-butyloxycarbonyl (Boc) protecting group on the amino group and a methyl ester group on the carboxylic acid. This compound serves as a valuable building block in the synthesis of peptides and peptidomimetics due to its stability and compatibility with solid-phase peptide synthesis (SPPS) methodologies. The Boc protecting group shields the amino group from unwanted reactions during peptide chain assembly, while the methyl ester group serves as a temporary protection for the carboxylic acid, which can be easily removed under mild conditions. N-Boc-glycine-methyl-ester is widely used in the pharmaceutical industry and academic research for the development of bioactive compounds and drug candidates.

Reference

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