Additional information
Description | N-Boc-glycine-methyl-ester is a chemical compound commonly used in peptide synthesis and organic chemistry. It is derived from glycine, the simplest amino acid, and features a tert-butyloxycarbonyl (Boc) protecting group on the amino group and a methyl ester group on the carboxylic acid. This compound serves as a valuable building block in the synthesis of peptides and peptidomimetics due to its stability and compatibility with solid-phase peptide synthesis (SPPS) methodologies. The Boc protecting group shields the amino group from unwanted reactions during peptide chain assembly, while the methyl ester group serves as a temporary protection for the carboxylic acid, which can be easily removed under mild conditions. N-Boc-glycine-methyl-ester is widely used in the pharmaceutical industry and academic research for the development of bioactive compounds and drug candidates. |
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Reference | 1) Organocatalysis in Continuous Flow for Drug Discovery |