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Tauro-Obeticholic Acid-d4

Catalog No. AN-14281
Name Tauro 6-Ethylchenodeoxycholic Acid-d4
Synonyms 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid-d4
CAS No. 863239-61-6 (unlabeled)
Purity 98+%
Formula C28H45D4NO6S
Mol. Weight 531.78
Storage -20°C Freezer, Under Inert Atmosphere
Appearance Solid
MSDS Inquire

$105.00$650.00

Additional information

Description

Tauro-obeticholic acid, an active metabolite of obeticholic acid, functions as an agonist of the farnesoid X receptor (FXR) and is derived from chenodeoxycholic acid through semisynthesis [1]. It undergoes formation via taurine conjugation in the liver and can revert to obeticholic acid through enzymatic action by intestinal microflora.

Reference

1) Markham, A., and Keam, S.J. Obeticholic acid: First global approval. Drugs 76(12), 1221-1226 (2016).