| Catalog No. | AN-14278 |
|---|---|
| Name | 2-[[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid |
| Synonyms | Tauro-Obeticholic acid, Obeticholic Acid Taurine Conjugate,Tauro 6-Ethylchenodeoxycholic Acid |
| CAS No. | 863239-61-6 |
| Purity | 98+% |
| Formula | C28H49NO6S |
| Mol. Weight | 527.8 |
| Storage | -20°C Freezer, Under Inert Atmosphere |
| Appearance | Solid |
| MSDS | Inquire |
$250.00 – $1,050.00
| Description | Tauro-obeticholic acid, an active metabolite of obeticholic acid, functions as an agonist of the farnesoid X receptor (FXR) and is derived from chenodeoxycholic acid through semisynthesis [1]. It undergoes formation via taurine conjugation in the liver and can revert to obeticholic acid through enzymatic action by intestinal microflora. |
|---|---|
| Reference | [1] Markham, A., and Keam, S.J. Obeticholic acid: First global approval. Drugs 76(12), 1221-1226 (2016). |
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