Calcipotriol impurity F is a synthetic analogs of vitamin D that was studied for its potential antitumor effects. Studies has shown the combined treatment with vitamin D analog (24R)-Calcipotriene was more effective than the treatment with cytostatics applied alone. (24R)-Calcipotriene is also the 24-R epimer of Calcipotriene.
Rumbo, A., et al.: J. Steroid. Biochem. Molec. Biol., 121, 68 (2010); Calverley, M.J., et al.: Tetrahedron, 43, 4609 (1987).