Additional information
| Description | Impurity F of Calcipotriol, also known as Calcipotriene or MC 903, acts as a ligand for VDR-like receptors. It shows minimal impact on calcium homeostasis with an IC50 value. This compound regulates cell differentiation and proliferation. Calcipotriol demonstrates antiproliferative effects against various cancer cell lines, including human HL-60, HL60/MX2, MCF-7, T47D, SCC-25, and mouse WEHI-3 cells.[1,2] |
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| References | [1]. Binderup (1993) Comparison of calcipotriol with selected metabolites and analogues of vitamin D3: effects on cell growth regulation in vitro and calcium metabolism in vivo. Pharmacol.Toxicol. 72 240. |
