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Calcipotriol Impurity F

Catalog No. V09127
Name Calcipotriol Impurity F
Synonyms (1a,3b,5Z,7E,22E,24S)-lethyl)dimethylsilyl]oxy]-9,109),22-tetraen-24-ol; (aS)-a-[(1E,3R)-3-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene;1,3-Bis-O-(tert-butyldimethylsilyl)calcipotriene
CAS No. 112875-61-3
Purity 99+%
Formula
C39H68O3Si2
Mol. Weight 641.13
Storage -20°C Freezer
Appearance White solid
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Description

Calcipotriol impurity F is a synthetic analogs of vitamin D that was studied for its potential antitumor effects. Studies has shown the combined treatment with vitamin D analog (24R)-Calcipotriene was more effective than the treatment with cytostatics applied alone. (24R)-Calcipotriene is also the 24-R epimer of Calcipotriene.

References

Rumbo, A., et al.: J. Steroid. Biochem. Molec. Biol., 121, 68 (2010); Calverley, M.J., et al.: Tetrahedron, 43, 4609 (1987).