Product Search:

13-Cis-Acitretin

Catalog No. V09144
Name 13-Cis-Acitretin
Synonyms 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4, USP Acitretin Related Compound A,6,8-nonatetraenoic Acid, 13-cis-Etretin, Isoacitretin, Isoetretin, Ro 13-7652
CAS No. 69427-46-9
Purity 99+%
Formula C21H26O3
Mol. Weight 326.43
Storage -20°C Freezer
Appearance Yellow Solid
MSDS Inquire

$50.00 – $325.00

Clear
SKU: N/A Categories: , Tags: ,

Additional information

Description

13-cis-Acitretin is cis isomer of acitretin, a retinoid that binds to nuclear receptors and regulates gene expression, is a potent activator of the α-secretase ADAM10 gene expression and apoptosis inducer via the CD95 signalling pathway. Acitretin is a systemic retinoid drug used in the treatment of severe psoriasis.
References

1. Berbis Ph, et al.: Arch Dermatol Res (1988) 280:388-389.
2. Maier H, Honigsmann H: Concentration of etretinate in plasma and subcutaneous fat after long-term acitretin. Lancet 348:1107, 1996.
3. Geiger JM, Walker M: Is there a reproductive safety risk in male patients treated with acitretin (Neotigason/ Soriatane)? Dermatology 205:105-107, 2002.

Related products