Additional information
| Description | Biotin-PEG2-Amine is a biotin derivative soluble in water, designed for easy coupling with activated carboxylic acids. The amino-PEO tether enhances its water solubility, and its extended chain length (20.4 Å) enhances binding to avidin. When conjugated to substrates, it improves the aqueous solubility of the complex. This compound is commonly employed in the affinity purification of oligonucleotides. |
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| Reference | [1] Chemical modification-assisted bisulfite sequencing (CAB-Seq) for 5-carboxylcytosine detection in DNA., Lu, X., et al. 2013. J Am Chem Soc. 135: 9315-7. PMID: 23758547 |
