Product Search:

Biotin

Biotin

Catalog No. B-22001
Name Biotin
Synonyms (3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid; D-Biotin NSC 63865 Vitamin B7
CAS No. 58-85-5
Purity 98+%
Formula C10H16N2O3S
Mol. Weight 244.3
Storage -20°C
Appearance Crystalline solid
MSDS Inquire

 

Price range: $30.00 through $170.00

SKU: N/A Category:

Additional information

Description

Biotin serves as a crucial coenzyme for specific carboxylases and is integral in modifying histones to regulate gene transcription [1,2,3]. Biotin-dependent carboxylases contribute to fatty acid and amino acid synthesis, as well as gluconeogenesis [1]. Beyond its metabolic roles, biotin finds applications in biotechnology, including DNA hybridization, flow cytometry, affinity purification, and the identification of protein-protein interactions and post-translational modifications [4].
Reference

[1] Tong, L. Structure and function of biotin-dependent carboxylases. Cell Mol. Life Sci. 70(5), 863-891 (2013).
[2] Mock, D.M. Biotin: From Nutrition to Therapeutics. J. Nutr. (2017).
[3] Zempleni, J., Teixeira, D.C., Kuroishi, T., et al. Biotin requirements for DNA damage prevention. Mutat. Res. 733(1-2), 58-60 (2012).
[4] Dundas, C.M., Demonte, D., and Park, S. Streptavidin-biotin technology: Improvements and innovations in chemical and biological applications. Appl. Microbiol. Biotechnol. 97(21), 9343-9353 (2013).

Related products