Additional information
| Description | Biotin-LC-LC-NHS is a biotinylation reagent featuring an N-hydroxysuccinimide (NHS) group that activates carboxylic acid groups on biotin, enabling efficient coupling reactions. With a 30.5 Å spacer, it minimizes steric hindrance during conjugation processes [1]. This reagent has been successfully employed to biotinylate small molecules like paclitaxel (Item No. 10461) and coenzyme Q10 (Item No. 11506), facilitating their characterization for binding site studies [1, 2]. |
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| Reference | [1] Lis, L.G., Smart, M.A., Luchniak, A., et al. Synthesis and biological evaluation of a biotinylated paclitaxel with an extra-long chain spacer arm. ACS Med. Chem. Lett. 3(9), 745-748 (2012). |
