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(+)-Biotinamidohexanoic acid hydrazide

Catalog No. B-22004
Name (+)-Biotinamidohexanoic acid hydrazide
Synonyms (+)-Biotin-ε-aminocaproyl hydrazide, (+)-Biotin-X-hydrazide, (+)-Biotinamidocaproyl hydrazide, BACH, N-(+)-Biotinyl-6-aminohexanoic hydrazide
CAS No. 109276-34-8
Purity 98+%
Formula C16H29N5O3S
Mol. Weight 371.50
Storage -20°C
Appearance Crystalline solid
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Additional information

Description

Biotin LC hydrazide serves as a reactive probe essential for biotinylating carboxyl or vicinal hydroxyl groups on carbohydrates, glycoproteins, or other glycoconjugates [1]. This versatile compound is also utilized in linking biotin to antibodies and ribonucleotides [1, 2]. Featuring an elongated spacer arm, Biotin LC hydrazide effectively minimizes steric hindrances, ensuring efficient coupling reactions in diverse biological contexts.

Reference

[1] Diamandis, E.P., and Christopoulos, T.K. The biotin-(strept)avidin system: Principles and applications in biotechnology. Clin. Chem. 37(5), 625-636 (1991).
[2] Haugland, R.P., and You, W.W. Coupling of antibodies with biotin. Methods Mol. Biol. 418, 13-23 (2008).