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4-OH Propranolol HCl D7

Catalog no. AN-14145
Name 4-OH Propranolol HCl D7
CAS No. 1219908-86-7
Synonyms (±)-4-Hydroxypropranolol-d7 HCl; rac-4-Hydroxy Propranolol-d7 Hydrochloride; 4-[2-Hydroxy-3-[(1-methylethyl-d7)amino]propoxy]-1-naphthalenol Hydrochloride
Purity 99+%
Formula C16H14NO3D7.HCl
FW 318.85
Storage  -20°C Freezer
Appearance A crystalline solid
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Additional information

Biological Activity

A deuterated labelled internal standard metabolite of propranolol. (±)-4-hydroxy Propranolol is an active metabolite of propranolol, inhibiting β1- and β2-adrenergic receptors with KD values of 2.4 and 5.8 nM, respectively.3,4 It is comparable to propranolol in potency in antagonizing the effects of isoprenaline on heart rate and blood pressure in cats and dogs.3,5 (±)-4-hydroxy Propranolol also has antioxidant properties at micromolar concentrations.


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